| 2020-11-25 | @ | Oakland | W | 101-49 | |
| 2020-11-26 | @ | Bradley | W | 51-50 | |
| 2020-11-27 | @ | Toledo | W | 76-73 | |
| 2020-11-30 | @ | Eastern Ky. | W | 99-96 | OT |
| 2020-12-02 | @ | Tennessee Tech | W | 79-48 | |
| 2020-12-06 | vs. | Cincinnati | W | 69-77 | |
| 2020-12-09 | @ | Oklahoma | W | 99-77 | |
| 2020-12-20 | @ | Marquette | W | 91-88 | |
| 2020-12-23 | vs. | Creighton | L | 66-61 | |
| 2020-12-30 | @ | Seton Hall | L | 68-85 | |
| 2021-01-06 | @ | St. John's (NY) | W | 69-61 | |
| 2021-01-10 | @ | Providence | W | 74-73 | |
| 2021-01-13 | @ | Villanova | |||
| 2021-01-16 | vs. | Seton Hall | |||
| 2021-01-20 | vs. | UConn | |||
| 2021-01-26 | @ | Georgetown | |||
| 2021-01-29 | vs. | Butler | |||
| 2021-02-03 | vs. | DePaul | |||
| 2021-02-07 | vs. | Villanova | |||
| 2021-02-11 | @ | DePaul | |||
| 2021-02-13 | @ | UConn |