| 2020-11-27 | vs. | Little Rock | W | 70-77 | |
| 2020-12-01 | @ | Winthrop | L | 67-75 | |
| 2020-12-02 | vs. | Duquesne | L | 81-68 | |
| 2020-12-10 | vs. | Coppin St. | L | 85-80 | |
| 2020-12-13 | @ | Norfolk St. | W | 64-47 | |
| 2020-12-15 | @ | USC Upstate | W | 65-57 | |
| 2020-12-19 | vs. | Elon | W | 64-71 | |
| 2020-12-22 | vs. | North Carolina A&T | W | 65-86 | |
| 2021-01-02 | @ | ETSU | L | 61-71 | |
| 2021-01-06 | vs. | Wofford | W | 75-84 | |
| 2021-01-09 | @ | Wofford | L | 45-48 | |
| 2021-01-14 | vs. | Samford | W | 63-87 | |
| 2021-01-16 | vs. | Samford | W | 70-82 | |
| 2021-01-18 | @ | The Citadel | W | 87-73 | |
| 2021-01-23 | vs. | Chattanooga | W | 66-74 | |
| 2021-01-27 | @ | Mercer | W | 81-68 | |
| 2021-01-30 | @ | VMI | W | 76-59 | |
| 2021-02-03 | vs. | The Citadel | W | 66-85 | |
| 2021-02-08 | vs. | Furman | L | 68-49 | |
| 2021-02-10 | @ | Furman | W | 64-58 | |
| 2021-02-13 | vs. | Mercer | W | 74-77 | |
| 2021-02-17 | vs. | VMI | L | 88-77 | |
| 2021-02-20 | @ | Chattanooga | W | 60-55 | |
| 2021-02-22 | vs. | Western Caro. | W | 56-77 | |
| 2021-02-24 | @ | Western Caro. | L | 80-81 | |
| 2021-02-27 | vs. | ETSU | W | 74-85 | OT |
| 2021-03-06 | @ | The Citadel | W | 80-72 | |
| 2021-03-07 | @ | ETSU | W | 77-65 | |
| 2021-03-08 | @ | Mercer | W | 69-61 | |
| 2021-03-20 | vs. | Florida St. | L | 64-54 |