| 2020-11-27 | @ | Lamar University | W | 66-57 | |
| 2020-11-29 | @ | Lipscomb | W | 68-66 | |
| 2020-12-09 | @ | Southern Miss. | W | 58-38 | |
| 2020-12-12 | @ | Ark.-Pine Bluff | W | 67-56 | |
| 2020-12-16 | @ | Memphis | L | 74-80 | |
| 2020-12-19 | @ | Grambling | W | 77-65 | |
| 2020-12-22 | vs. | East Carolina | L | 68-58 | |
| 2021-01-02 | @ | East Carolina | W | 60-56 | |
| 2021-01-09 | vs. | Houston | L | 71-50 | |
| 2021-01-16 | @ | Temple | L | 57-65 | |
| 2021-01-28 | @ | Houston | L | 60-83 | |
| 2021-01-31 | vs. | Temple | W | 64-81 | |
| 2021-02-03 | vs. | Wichita St. | L | 75-67 | |
| 2021-02-07 | @ | Cincinnati | L | 61-64 | |
| 2021-02-10 | vs. | Tulsa | W | 48-58 | |
| 2021-02-12 | vs. | UCF | L | 53-49 | |
| 2021-02-14 | vs. | South Fla. | W | 59-62 | |
| 2021-02-20 | @ | UCF | L | 81-84 | |
| 2021-02-24 | vs. | Memphis | L | 61-46 | |
| 2021-02-26 | vs. | Cincinnati | L | 91-71 | |
| 2021-03-03 | @ | Wichita St. | L | 70-78 | |
| 2021-03-11 | vs. | Tulsa | W | 70-77 | |
| 2021-03-12 | vs. | Houston | L | 77-52 |