| 2020-12-15 | vs. | Akron | W | 74-81 | |
| 2020-12-19 | @ | Hofstra | W | 77-69 | |
| 2020-12-30 | vs. | Rhode Island | L | 63-57 | |
| 2021-01-02 | vs. | Richmond | W | 66-69 | |
| 2021-01-06 | @ | Saint Joseph's | W | 83-57 | |
| 2021-01-13 | vs. | Fordham | W | 54-68 | |
| 2021-01-15 | @ | Duquesne | W | 62-48 | |
| 2021-01-20 | @ | VCU | W | 70-54 | |
| 2021-01-23 | vs. | Duquesne | W | 61-65 | |
| 2021-01-30 | @ | George Mason | W | 84-67 | |
| 2021-02-06 | vs. | Saint Louis | L | 70-59 | |
| 2021-02-09 | @ | La Salle | W | 86-73 | |
| 2021-02-12 | vs. | VCU | L | 67-64 | |
| 2021-02-21 | @ | Davidson | W | 69-58 | |
| 2021-02-24 | vs. | Davidson | W | 53-56 | |
| 2021-02-26 | @ | George Washington | W | 88-41 | |
| 2021-03-01 | @ | Dayton | L | 52-55 | |
| 2021-03-05 | @ | Duquesne | W | 75-59 | |
| 2021-03-06 | @ | Saint Louis | W | 71-53 | |
| 2021-03-14 | @ | VCU | W | 74-65 | |
| 2021-03-20 | vs. | LSU | L | 76-61 |