| 2020-11-25 | vs. | SMU | L | 97-67 | |
| 2020-11-27 | vs. | Texas Tech | L | 84-52 | |
| 2020-11-29 | @ | Boise St. | L | 55-86 | |
| 2020-12-14 | vs. | LSU | L | 88-66 | |
| 2020-12-16 | vs. | Texas | L | 79-63 | |
| 2020-12-19 | @ | Rice | W | 82-69 | |
| 2020-12-21 | vs. | UTRGV | W | 66-69 | |
| 2021-01-02 | vs. | Nicholls St. | W | 81-84 | |
| 2021-01-06 | vs. | Southeastern La. | W | 52-70 | |
| 2021-01-09 | vs. | Central Ark. | W | 80-91 | |
| 2021-01-13 | @ | Lamar University | W | 96-71 | |
| 2021-01-16 | @ | Houston Baptist | W | 87-80 | |
| 2021-01-20 | @ | Abilene Christian | |||
| 2021-01-27 | vs. | TX A&M-Corpus Christi | |||
| 2021-01-31 | vs. | SFA | |||
| 2021-02-06 | @ | Nicholls St. | |||
| 2021-02-10 | @ | Southeastern La. | |||
| 2021-02-13 | @ | Central Ark. |