| 2020-11-25 | vs. | Missouri | L | 91-64 | |
| 2020-12-02 | vs. | Wichita St. | L | 85-80 | |
| 2020-12-08 | vs. | Oklahoma St. | L | 83-78 | |
| 2020-12-16 | vs. | Oklahoma | L | 79-65 | |
| 2020-12-20 | vs. | Arkansas | L | 87-76 | |
| 2021-01-02 | vs. | Omaha | W | 83-95 | |
| 2021-01-03 | vs. | Omaha | W | 75-86 | |
| 2021-01-08 | @ | North Dakota | L | 71-72 | |
| 2021-01-09 | @ | North Dakota | W | 74-57 | |
| 2021-01-15 | vs. | Denver | W | 84-88 | |
| 2021-01-16 | vs. | Denver | W | 82-91 | |
| 2021-01-23 | @ | UMKC | W | 60-58 | |
| 2021-01-24 | @ | UMKC | L | 76-81 | |
| 2021-02-05 | vs. | North Dakota St. | L | 61-54 | |
| 2021-02-06 | vs. | North Dakota St. | W | 74-80 | |
| 2021-02-13 | @ | South Dakota St. | W | 103-86 | |
| 2021-02-14 | @ | South Dakota St. | L | 80-95 | |
| 2021-02-20 | vs. | South Dakota | L | 86-84 | |
| 2021-02-27 | @ | Western Ill. | W | 85-81 | |
| 2021-02-28 | @ | Western Ill. | W | 95-59 | |
| 2021-03-07 | @ | North Dakota | W | 76-65 | |
| 2021-03-08 | vs. | South Dakota St. | W | 88-90 | |
| 2021-03-09 | vs. | North Dakota St. | W | 72-75 | |
| 2021-03-19 | vs. | Ohio St. | W | 72-75 | OT |
| 2021-03-21 | vs. | Florida | W | 78-81 | |
| 2021-03-27 | vs. | Arkansas | L | 72-70 |