| 2020-11-25 | vs. | Maryland | L | 85-67 | |
| 2020-11-28 | @ | William & Mary | W | 86-78 | |
| 2020-12-02 | vs. | Norfolk St. | W | 66-80 | |
| 2020-12-12 | vs. | VCU | L | 77-54 | |
| 2020-12-20 | @ | Northeastern | W | 66-62 | |
| 2021-01-01 | vs. | FIU | L | 82-67 | |
| 2021-01-02 | vs. | FIU | W | 66-71 | |
| 2021-01-08 | @ | Fla. Atlantic | W | 71-67 | |
| 2021-01-09 | @ | Fla. Atlantic | W | 64-55 | |
| 2021-01-15 | vs. | Rice | L | 69-59 | |
| 2021-01-16 | vs. | Rice | W | 58-61 | |
| 2021-02-05 | @ | Marshall | W | 82-81 | |
| 2021-02-06 | @ | Marshall | L | 67-87 | |
| 2021-02-10 | vs. | Charlotte | W | 76-78 | OT |
| 2021-02-13 | @ | Charlotte | W | 64-45 | |
| 2021-02-19 | vs. | UAB | L | 76-69 | |
| 2021-02-20 | vs. | UAB | W | 58-65 | |
| 2021-02-26 | @ | Middle Tenn. | W | 67-61 | |
| 2021-02-27 | @ | Middle Tenn. | W | 73-60 | |
| 2021-03-05 | vs. | Western Ky. | W | 69-71 | |
| 2021-03-06 | vs. | Western Ky. | L | 60-57 | |
| 2021-03-11 | @ | North Texas | L | 55-61 |