| 2020-11-25 | @ | Charleston So. | W | 95-61 | |
| 2020-11-27 | @ | North Florida | W | 86-51 | |
| 2020-12-03 | @ | UMass Lowell | W | 90-59 | |
| 2020-12-17 | vs. | Saint Louis | L | 80-69 | |
| 2020-12-19 | @ | Campbell | W | 69-50 | |
| 2020-12-22 | @ | North Carolina | W | 79-76 | |
| 2020-12-30 | @ | Boston College | W | 79-76 | |
| 2021-01-05 | vs. | Clemson | L | 74-70 | OT |
| 2021-01-09 | @ | Miami (FL) | L | 59-64 | |
| 2021-01-13 | vs. | Florida St. | L | 105-73 | |
| 2021-01-16 | @ | Georgia Tech | |||
| 2021-01-20 | vs. | Virginia | |||
| 2021-01-23 | vs. | North Carolina | |||
| 2021-01-27 | @ | Wake Forest | |||
| 2021-01-31 | vs. | Syracuse | |||
| 2021-02-03 | @ | Virginia | |||
| 2021-02-06 | vs. | Boston College | |||
| 2021-02-09 | @ | Syracuse |