| 2020-11-27 | vs. | James Madison | W | 73-83 | |
| 2020-11-28 | @ | Radford | W | 57-54 | |
| 2020-12-02 | @ | Old Dominion | L | 66-80 | |
| 2020-12-07 | @ | Hampton | W | 76-64 | |
| 2020-12-13 | vs. | UNCG | L | 64-47 | |
| 2020-12-18 | @ | UNCW | L | 72-80 | |
| 2020-12-26 | vs. | George Mason | W | 65-68 | |
| 2021-01-09 | @ | Morgan St. | L | 74-78 | |
| 2021-01-10 | @ | Morgan St. | W | 89-85 | |
| 2021-01-16 | vs. | Delaware St. | W | 76-87 | |
| 2021-01-17 | vs. | Delaware St. | W | 79-83 | OT |
| 2021-01-23 | vs. | Coppin St. | L | 81-71 | |
| 2021-01-24 | vs. | Coppin St. | L | 81-77 | |
| 2021-01-30 | @ | Delaware St. | W | 94-66 | |
| 2021-02-07 | @ | Coppin St. | W | 84-72 | |
| 2021-02-08 | @ | Coppin St. | L | 64-74 | |
| 2021-02-13 | vs. | Morgan St. | W | 69-74 | |
| 2021-02-14 | vs. | Morgan St. | W | 65-68 | |
| 2021-02-24 | @ | Delaware St. | W | 86-55 | |
| 2021-03-11 | @ | UNC Central | W | 87-58 | |
| 2021-03-18 | @ | Appalachian St. | W | 54-53 | |
| 2021-03-20 | vs. | Gonzaga | L | 98-55 |