| 2020-11-25 | @ | Austin Peay | L | 66-72 | |
| 2020-11-26 | vs. | Middle Tenn. | W | 59-60 | |
| 2020-11-28 | vs. | Abilene Christian | L | 70-58 | |
| 2020-12-01 | vs. | Creighton | L | 94-67 | |
| 2020-12-03 | vs. | Drake | L | 87-66 | |
| 2020-12-05 | vs. | SIUE | W | 63-65 | |
| 2020-12-11 | vs. | Kansas | L | 95-50 | |
| 2020-12-16 | vs. | Colorado | L | 91-49 | |
| 2020-12-17 | vs. | Wyoming | L | 82-78 | |
| 2020-12-29 | vs. | Kansas St. | L | 60-58 | |
| 2021-01-02 | @ | Oral Roberts | L | 83-95 | |
| 2021-01-03 | @ | Oral Roberts | L | 75-86 | |
| 2021-01-08 | vs. | North Dakota St. | L | 71-69 | |
| 2021-01-09 | vs. | North Dakota St. | L | 80-66 | |
| 2021-01-29 | vs. | South Dakota | L | 91-59 | |
| 2021-01-30 | vs. | South Dakota | L | 97-93 | |
| 2021-02-05 | @ | Western Ill. | L | 77-85 | |
| 2021-02-06 | @ | Western Ill. | L | 73-75 | |
| 2021-02-12 | vs. | UMKC | L | 62-52 | |
| 2021-02-13 | vs. | UMKC | L | 55-47 | |
| 2021-02-19 | @ | North Dakota | W | 72-62 | |
| 2021-02-20 | @ | North Dakota | L | 69-81 | |
| 2021-02-26 | vs. | Denver | W | 76-80 | |
| 2021-02-27 | vs. | Denver | W | 76-80 | |
| 2021-03-06 | vs. | South Dakota St. | L | 84-71 |