| 2020-11-25 | @ | George Washington | W | 78-71 | |
| 2020-11-27 | vs. | Maryland | L | 82-52 | |
| 2020-11-28 | vs. | Mt. St. Mary's | W | 67-73 | |
| 2020-12-01 | vs. | Georgetown | W | 71-78 | |
| 2021-01-02 | @ | Bucknell | W | 78-69 | |
| 2021-01-03 | vs. | Bucknell | W | 60-63 | |
| 2021-01-09 | vs. | Lehigh | W | 61-69 | |
| 2021-01-10 | @ | Lehigh | W | 73-58 | |
| 2021-01-16 | @ | American | W | 87-86 | OT |
| 2021-01-17 | @ | American | W | 71-59 | |
| 2021-01-23 | @ | Army | W | 69-62 | |
| 2021-01-24 | @ | Army | L | 78-87 | OT |
| 2021-01-30 | @ | Loyola Maryland | W | 70-52 | |
| 2021-02-20 | vs. | American | W | 60-72 | |
| 2021-02-21 | vs. | American | W | 60-69 | |
| 2021-02-27 | vs. | Loyola Maryland | W | 67-73 | |
| 2021-02-28 | @ | Loyola Maryland | W | 66-58 | |
| 2021-03-06 | @ | Loyola Maryland | L | 68-76 |