| 2020-12-02 | vs. | Middle Tenn. | L | 78-61 | |
| 2020-12-05 | @ | Illinois St. | W | 76-65 | |
| 2020-12-08 | @ | Austin Peay | W | 87-57 | |
| 2020-12-11 | vs. | Southern Ill. | L | 70-66 | |
| 2020-12-21 | vs. | Austin Peay | L | 74-70 | |
| 2020-12-30 | vs. | Belmont | L | 68-55 | |
| 2021-01-02 | @ | Morehead St. | L | 56-61 | |
| 2021-01-07 | vs. | Eastern Ill. | L | 74-68 | |
| 2021-01-09 | vs. | SIUE | |||
| 2021-01-16 | vs. | UT Martin | |||
| 2021-01-21 | @ | Jacksonville St. | |||
| 2021-01-23 | @ | Tennessee Tech | |||
| 2021-01-28 | @ | Tennessee St. | |||
| 2021-01-30 | @ | Belmont | |||
| 2021-02-04 | vs. | Morehead St. | |||
| 2021-02-06 | vs. | Eastern Ky. | |||
| 2021-02-11 | @ | Southeast Mo. St. |