| 2020-12-19 | @ | Northwestern St. | W | 94-67 | |
| 2020-12-21 | @ | Little Rock | W | 85-77 | |
| 2020-12-27 | vs. | UNI | W | 59-79 | |
| 2020-12-28 | vs. | UNI | L | 85-75 | |
| 2021-01-02 | @ | Indiana St. | W | 84-74 | |
| 2021-01-03 | @ | Indiana St. | W | 70-66 | |
| 2021-01-09 | vs. | Valparaiso | W | 68-81 | |
| 2021-01-10 | vs. | Valparaiso | W | 68-78 | |
| 2021-01-26 | @ | Drake | L | 61-68 | |
| 2021-01-27 | @ | Drake | L | 73-78 | |
| 2021-01-31 | @ | Loyola Chicago | L | 46-72 | |
| 2021-02-01 | @ | Loyola Chicago | L | 50-70 | |
| 2021-02-06 | vs. | Illinois St. | W | 67-74 | |
| 2021-02-07 | vs. | Illinois St. | W | 62-72 | |
| 2021-02-10 | @ | Southern Ill. | W | 65-53 | |
| 2021-02-13 | @ | Bradley | W | 80-58 | |
| 2021-02-14 | @ | Bradley | W | 72-57 | |
| 2021-02-17 | vs. | Southern Ill. | W | 53-68 | |
| 2021-02-26 | vs. | Evansville | W | 81-90 | |
| 2021-02-27 | vs. | Evansville | L | 72-63 | |
| 2021-03-05 | @ | Valparaiso | W | 66-55 | |
| 2021-03-06 | vs. | Drake | L | 71-69 |