| 2020-11-25 | @ | North Dakota | W | 81-67 | |
| 2020-12-05 | vs. | Wright St. | L | 71-47 | |
| 2020-12-09 | @ | Western Ill. | W | 67-57 | |
| 2020-12-15 | @ | Buffalo | L | 62-90 | |
| 2020-12-19 | vs. | Bradley | L | 69-68 | |
| 2021-01-09 | @ | Northern Ill. | W | 70-58 | |
| 2021-01-12 | vs. | Ohio | L | 78-61 | |
| 2021-01-19 | @ | Ball St. | W | 81-71 | |
| 2021-01-21 | @ | Bowling Green | W | 96-77 | |
| 2021-01-23 | vs. | Eastern Mich. | W | 63-85 | |
| 2021-01-26 | @ | Toledo | L | 81-90 | |
| 2021-01-30 | @ | Western Mich. | W | 65-56 | |
| 2021-02-02 | vs. | Kent St. | L | 77-68 | |
| 2021-02-06 | vs. | Buffalo | L | 88-64 | |
| 2021-02-12 | @ | Akron | L | 76-83 | |
| 2021-02-16 | vs. | Toledo | L | 87-75 | |
| 2021-02-20 | vs. | Northern Ill. | W | 64-69 | |
| 2021-02-23 | vs. | Central Mich. | W | 54-96 | |
| 2021-02-25 | vs. | Western Mich. | W | 66-74 | |
| 2021-02-27 | @ | Kent St. | L | 51-64 | |
| 2021-03-02 | vs. | Bowling Green | W | 79-84 | OT |
| 2021-03-11 | vs. | Buffalo | L | 74-63 |