| 2020-11-27 | @ | UT Arlington | W | 76-71 | |
| 2020-11-29 | @ | Northwestern St. | W | 91-77 | |
| 2020-12-03 | @ | La.-Monroe | W | 78-62 | |
| 2020-12-06 | vs. | LSU | L | 86-55 | |
| 2020-12-09 | @ | Southeastern La. | W | 78-69 | |
| 2020-12-12 | vs. | Louisiana | L | 61-56 | |
| 2020-12-15 | @ | Jackson St. | W | 85-58 | |
| 2020-12-19 | @ | Lamar University | W | 86-57 | |
| 2020-12-22 | vs. | La.-Monroe | W | 57-68 | |
| 2021-01-01 | @ | Marshall | W | 75-68 | |
| 2021-01-02 | @ | Marshall | L | 73-80 | |
| 2021-01-08 | vs. | Western Ky. | L | 66-64 | |
| 2021-01-09 | vs. | Western Ky. | W | 58-63 | |
| 2021-01-15 | @ | UTSA | W | 77-66 | |
| 2021-01-16 | @ | UTSA | W | 82-66 | |
| 2021-01-22 | vs. | UTEP | L | 82-74 | |
| 2021-01-23 | vs. | UTEP | W | 55-73 | |
| 2021-01-28 | vs. | Southern Miss. | W | 63-76 | |
| 2021-01-30 | @ | Southern Miss. | W | 65-62 | |
| 2021-02-05 | vs. | North Texas | W | 63-68 | |
| 2021-02-06 | vs. | North Texas | L | 57-55 | |
| 2021-02-12 | @ | UAB | W | 70-58 | |
| 2021-02-13 | @ | UAB | W | 69-64 | |
| 2021-02-26 | @ | Rice | W | 101-57 | |
| 2021-02-27 | @ | Rice | W | 79-58 | |
| 2021-03-11 | @ | Fla. Atlantic | W | 75-69 | |
| 2021-03-12 | @ | North Texas | L | 48-54 | |
| 2021-03-19 | vs. | Ole Miss | W | 61-70 | |
| 2021-03-25 | vs. | Western Ky. | W | 65-72 | |
| 2021-03-27 | vs. | Mississippi St. | L | 84-62 | |
| 2021-03-28 | vs. | Colorado St. | W | 74-76 |