| 2020-11-27 | vs. | Wake Forest | L | 71-60 | |
| 2020-12-01 | vs. | VMI | L | 84-71 | |
| 2020-12-08 | @ | North Carolina A&T | W | 77-60 | |
| 2020-12-14 | vs. | Radford | L | 67-66 | |
| 2020-12-15 | vs. | Radford | L | 62-53 | |
| 2020-12-19 | @ | The Citadel | L | 89-91 | |
| 2020-12-21 | vs. | Virginia Tech | L | 84-58 | |
| 2020-12-30 | @ | UNC Asheville | L | 73-80 | |
| 2020-12-31 | @ | UNC Asheville | W | 65-55 | |
| 2021-01-04 | vs. | USC Upstate | L | 71-69 | |
| 2021-01-05 | vs. | USC Upstate | L | 65-59 | |
| 2021-01-09 | @ | Campbell | L | 58-64 | |
| 2021-01-10 | @ | Campbell | W | 78-69 | |
| 2021-01-14 | vs. | Winthrop | L | 72-61 | |
| 2021-01-15 | vs. | Winthrop | L | 70-50 | |
| 2021-01-19 | @ | High Point | W | 75-54 | |
| 2021-01-20 | @ | High Point | W | 67-54 | |
| 2021-01-29 | vs. | Presbyterian | W | 45-49 | |
| 2021-01-30 | vs. | Presbyterian | L | 66-54 | |
| 2021-02-11 | @ | Gardner-Webb | W | 57-54 | |
| 2021-02-12 | @ | Gardner-Webb | W | 78-71 | |
| 2021-02-15 | @ | Hampton | W | 83-73 | |
| 2021-02-18 | vs. | Charleston So. | W | 62-70 | |
| 2021-02-19 | vs. | Charleston So. | W | 58-64 | |
| 2021-02-24 | @ | Hampton | L | 68-74 | |
| 2021-03-01 | vs. | UNC Asheville | W | 61-77 | |
| 2021-03-04 | vs. | Winthrop | L | 82-61 | |
| 2021-03-22 | vs. | Pepperdine | L | 80-66 |