| 2020-11-25 | vs. | Houston | L | 89-45 | |
| 2020-11-27 | vs. | Tulane | L | 66-57 | |
| 2020-11-28 | @ | Lipscomb | L | 73-76 | |
| 2020-12-05 | vs. | Air Force | L | 59-44 | |
| 2020-12-09 | vs. | La.-Monroe | W | 60-63 | |
| 2020-12-15 | @ | Southern Miss. | L | 63-66 | |
| 2020-12-19 | vs. | Louisiana Tech | L | 86-57 | |
| 2020-12-22 | vs. | UTSA | L | 88-66 | |
| 2020-12-29 | @ | Southeastern La. | W | 74-64 | |
| 2021-01-02 | vs. | Abilene Christian | L | 83-65 | |
| 2021-01-06 | vs. | Nicholls St. | L | 76-69 | |
| 2021-01-09 | @ | Houston Baptist | W | 71-65 | |
| 2021-01-13 | vs. | Sam Houston St. | L | 96-71 | |
| 2021-01-23 | vs. | SFA | L | 102-72 | |
| 2021-01-30 | @ | McNeese | W | 64-56 | |
| 2021-02-06 | @ | Abilene Christian | L | 62-77 | |
| 2021-02-10 | @ | Nicholls St. | L | 71-76 | |
| 2021-02-13 | vs. | Houston Baptist | L | 80-75 | |
| 2021-02-20 | vs. | TX A&M-Corpus Christi | L | 77-68 | |
| 2021-02-22 | @ | Sam Houston St. | L | 71-77 | |
| 2021-02-27 | @ | SFA | W | 88-83 | 2OT |
| 2021-03-01 | @ | TX A&M-Corpus Christi | W | 66-47 | |
| 2021-03-06 | vs. | McNeese | W | 51-60 | |
| 2021-03-10 | @ | Houston Baptist | W | 62-52 | |
| 2021-03-11 | vs. | Sam Houston St. | W | 69-70 | |
| 2021-03-12 | vs. | Abilene Christian | L | 93-71 |