| 2021-01-02 | vs. | Lehigh | L | 90-89 | OT |
| 2021-01-03 | @ | Lehigh | W | 82-70 | |
| 2021-01-09 | vs. | Bucknell | W | 60-83 | |
| 2021-01-10 | @ | Bucknell | W | 87-76 | |
| 2021-01-16 | @ | Loyola Maryland | W | 77-75 | |
| 2021-01-17 | vs. | Loyola Maryland | W | 70-72 | |
| 2021-01-23 | @ | Boston U. | L | 76-81 | |
| 2021-01-24 | @ | Boston U. | L | 61-64 | |
| 2021-02-07 | vs. | Loyola Maryland | L | 75-62 | |
| 2021-02-08 | @ | Loyola Maryland | W | 80-76 | |
| 2021-02-13 | @ | Loyola Maryland | W | 97-94 | 3OT |
| 2021-02-14 | vs. | Loyola Maryland | L | 88-69 | |
| 2021-02-27 | @ | Lehigh | W | 75-69 | |
| 2021-02-28 | vs. | Lehigh | W | 70-71 | |
| 2021-03-06 | @ | Bucknell | L | 84-92 |