| 2020-12-04 | vs. | Virginia | L | 71-64 | OT |
| 2020-12-08 | vs. | Detroit Mercy | W | 66-80 | |
| 2020-12-13 | @ | Northern Ky. | W | 92-73 | |
| 2021-01-01 | vs. | Akron | L | 66-62 | |
| 2021-01-05 | @ | Toledo | L | 82-84 | |
| 2021-01-09 | @ | Western Mich. | W | 80-54 | |
| 2021-01-12 | vs. | Central Mich. | W | 85-94 | |
| 2021-01-16 | vs. | Ohio | W | 79-89 | |
| 2021-01-19 | @ | Buffalo | W | 84-81 | |
| 2021-01-23 | vs. | Toledo | L | 76-74 | |
| 2021-01-27 | @ | Bowling Green | W | 96-91 | |
| 2021-01-30 | @ | Central Mich. | W | 83-76 | |
| 2021-02-02 | @ | Miami (OH) | W | 77-68 | |
| 2021-02-05 | @ | Akron | L | 61-72 | |
| 2021-02-09 | vs. | Bowling Green | W | 67-71 | |
| 2021-02-13 | @ | Northern Ill. | W | 80-58 | |
| 2021-02-16 | vs. | Western Mich. | W | 69-76 | |
| 2021-02-20 | @ | Eastern Mich. | W | 64-51 | |
| 2021-02-24 | vs. | Ball St. | L | 90-71 | |
| 2021-02-27 | vs. | Miami (OH) | W | 51-64 | |
| 2021-03-05 | vs. | Buffalo | L | 81-67 | |
| 2021-03-11 | @ | Ohio | L | 63-85 |