| 2020-12-02 | vs. | UAB | L | 73-48 | |
| 2020-12-04 | vs. | Creighton | L | 93-58 | |
| 2020-12-16 | vs. | Belmont | L | 64-53 | |
| 2020-12-19 | @ | Samford | L | 63-65 | |
| 2020-12-22 | @ | Mercer | L | 71-81 | |
| 2021-01-01 | @ | Jacksonville | L | 57-62 | |
| 2021-01-02 | @ | Jacksonville | L | 66-72 | |
| 2021-01-08 | vs. | Liberty | L | 69-63 | |
| 2021-01-09 | vs. | Liberty | L | 76-47 | |
| 2021-01-15 | @ | North Alabama | L | 43-66 | |
| 2021-01-16 | @ | North Alabama | L | 64-66 | |
| 2021-01-22 | vs. | North Florida | L | 69-54 | |
| 2021-01-23 | vs. | North Florida | L | 68-65 | |
| 2021-01-29 | @ | Bellarmine | L | 67-84 | |
| 2021-01-30 | @ | Bellarmine | L | 79-84 | |
| 2021-02-12 | @ | Stetson | L | 61-74 | |
| 2021-02-13 | @ | Stetson | W | 83-75 | |
| 2021-02-19 | vs. | Lipscomb | L | 76-62 | |
| 2021-02-20 | vs. | Lipscomb | L | 77-63 | |
| 2021-02-26 | vs. | FGCU | W | 63-80 | |
| 2021-03-04 | vs. | Liberty | L | 69-59 |