| 2020-11-29 | @ | Ark.-Pine Bluff | W | 80-63 | |
| 2020-12-02 | @ | South Dakota St. | L | 68-71 | |
| 2020-12-11 | vs. | Iowa | L | 105-77 | |
| 2020-12-15 | @ | Kansas St. | L | 65-74 | |
| 2020-12-18 | vs. | West Virginia | L | 70-65 | |
| 2020-12-20 | @ | Jackson St. | W | 60-45 | |
| 2021-01-02 | @ | Baylor | L | 65-76 | |
| 2021-01-05 | vs. | Texas | L | 78-72 | |
| 2021-01-09 | @ | Texas Tech | L | 64-91 | |
| 2021-01-13 | vs. | Kansas St. | |||
| 2021-01-16 | vs. | Kansas | |||
| 2021-01-20 | @ | Texas | |||
| 2021-01-23 | vs. | Texas Tech | |||
| 2021-01-25 | @ | Oklahoma St. | |||
| 2021-01-30 | vs. | Mississippi St. | |||
| 2021-02-02 | @ | West Virginia | |||
| 2021-02-06 | vs. | Oklahoma | |||
| 2021-02-09 | vs. | TCU |