| 2020-12-12 | vs. | Purdue | L | 80-68 | |
| 2020-12-15 | vs. | Saint Louis | L | 78-59 | |
| 2020-12-19 | @ | Ball St. | W | 67-57 | |
| 2020-12-22 | @ | Southeast Mo. St. | W | 72-66 | |
| 2020-12-27 | @ | Drake | L | 63-81 | |
| 2020-12-28 | @ | Drake | L | 66-73 | |
| 2021-01-02 | vs. | Missouri St. | L | 84-74 | |
| 2021-01-03 | vs. | Missouri St. | L | 70-66 | |
| 2021-01-10 | @ | Loyola Chicago | W | 76-71 | |
| 2021-01-11 | @ | Loyola Chicago | L | 48-58 | |
| 2021-01-16 | vs. | Illinois St. | W | 65-73 | |
| 2021-01-17 | vs. | Illinois St. | W | 68-74 | |
| 2021-01-20 | @ | Evansville | |||
| 2021-01-25 | @ | Southern Ill. | |||
| 2021-01-26 | @ | Southern Ill. | |||
| 2021-01-31 | @ | Bradley | |||
| 2021-02-01 | @ | Bradley | |||
| 2021-02-06 | vs. | UNI | |||
| 2021-02-07 | vs. | UNI | |||
| 2021-02-13 | @ | Loyola Chicago |