| 2020-12-01 | vs. | George Washington | W | 78-82 | |
| 2020-12-07 | vs. | Norfolk St. | L | 76-64 | |
| 2020-12-13 | vs. | VMI | L | 79-64 | |
| 2020-12-16 | @ | William & Mary | L | 58-75 | |
| 2020-12-18 | vs. | Howard | L | 81-76 | |
| 2020-12-21 | vs. | Charleston So. | W | 55-67 | |
| 2020-12-22 | vs. | Charleston So. | W | 68-70 | |
| 2020-12-30 | @ | Gardner-Webb | W | 80-69 | |
| 2020-12-31 | @ | Gardner-Webb | L | 69-80 | |
| 2021-01-04 | vs. | Radford | L | 79-66 | |
| 2021-01-05 | vs. | Radford | L | 76-65 | |
| 2021-01-09 | @ | UNC Asheville | W | 73-71 | |
| 2021-01-10 | @ | UNC Asheville | L | 77-85 | |
| 2021-01-14 | vs. | USC Upstate | W | 68-69 | |
| 2021-01-15 | vs. | USC Upstate | W | 74-84 | |
| 2021-02-07 | @ | High Point | L | 58-72 | |
| 2021-02-08 | @ | High Point | W | 76-71 | |
| 2021-02-11 | @ | Presbyterian | L | 70-85 | |
| 2021-02-12 | @ | Presbyterian | W | 62-57 | |
| 2021-02-15 | vs. | Longwood | L | 83-73 | |
| 2021-02-18 | @ | Campbell | L | 57-76 | |
| 2021-02-19 | @ | Campbell | L | 68-73 | |
| 2021-02-24 | vs. | Longwood | W | 68-74 | |
| 2021-02-27 | @ | Presbyterian | W | 67-65 | |
| 2021-03-01 | vs. | Radford | L | 67-52 |