| 2020-11-25 | vs. | FGCU | L | 65-56 | |
| 2020-11-29 | vs. | Georgia | L | 85-75 | |
| 2020-12-09 | vs. | Oregon | L | 87-66 | |
| 2020-12-12 | vs. | Oklahoma | L | 85-54 | |
| 2020-12-15 | vs. | Austin Peay | W | 70-76 | |
| 2020-12-18 | vs. | Georgia Tech | L | 74-64 | |
| 2021-01-02 | vs. | South Carolina | L | 78-71 | |
| 2021-01-10 | @ | South Carolina St. | W | 70-68 | |
| 2021-01-30 | vs. | North Carolina A&T | L | 70-58 | |
| 2021-01-31 | vs. | North Carolina A&T | L | 67-65 | |
| 2021-02-08 | @ | UNC Central | W | 59-50 | |
| 2021-02-09 | @ | UNC Central | W | 60-47 | |
| 2021-02-20 | @ | North Carolina A&T | W | 71-57 | |
| 2021-02-21 | @ | North Carolina A&T | L | 63-70 | |
| 2021-02-25 | vs. | South Carolina St. | W | 67-75 | |
| 2021-02-27 | vs. | South Carolina St. | L | 63-57 | |
| 2021-02-28 | vs. | South Carolina St. | W | 58-63 | |
| 2021-03-03 | vs. | UNC Central | W | 58-65 | |
| 2021-03-04 | vs. | UNC Central | L | 74-71 | |
| 2021-03-11 | @ | Morgan St. | L | 75-77 |