| 2020-11-25 | vs. | Michigan St. | L | 83-67 | |
| 2020-12-04 | @ | Toledo | L | 74-91 | |
| 2020-12-29 | @ | Central Mich. | L | 60-87 | |
| 2021-01-09 | @ | Akron | W | 71-59 | |
| 2021-01-12 | vs. | Toledo | L | 96-63 | |
| 2021-01-16 | vs. | Central Mich. | L | 75-64 | |
| 2021-01-21 | vs. | Buffalo | L | 92-77 | |
| 2021-01-23 | @ | Miami (OH) | L | 63-85 | |
| 2021-01-26 | vs. | Akron | L | 86-65 | |
| 2021-02-20 | vs. | Kent St. | L | 64-51 | |
| 2021-02-23 | @ | Bowling Green | L | 69-82 | |
| 2021-02-25 | vs. | Ohio | L | 86-67 | |
| 2021-02-27 | @ | Northern Ill. | W | 91-57 | |
| 2021-03-02 | vs. | Ball St. | L | 100-65 | |
| 2021-03-05 | vs. | Western Mich. | W | 63-64 |