| 2020-11-25 | @ | North Florida | W | 80-67 | |
| 2020-11-27 | vs. | Charleston So. | W | 50-60 | |
| 2020-11-30 | vs. | Xavier | L | 99-96 | OT |
| 2020-12-02 | vs. | USC Upstate | W | 78-95 | |
| 2020-12-07 | @ | Morehead St. | W | 71-68 | |
| 2020-12-14 | vs. | Morehead St. | L | 75-62 | |
| 2020-12-22 | @ | High Point | W | 86-67 | |
| 2020-12-30 | @ | Eastern Ill. | W | 69-61 | |
| 2021-01-02 | vs. | Austin Peay | W | 75-80 | |
| 2021-01-07 | @ | Jacksonville St. | W | 69-66 | OT |
| 2021-01-09 | @ | Tennessee Tech | W | 90-80 | |
| 2021-01-16 | vs. | Eastern Ill. | W | 85-93 | OT |
| 2021-01-21 | @ | UT Martin | W | 113-73 | |
| 2021-02-02 | vs. | Jacksonville St. | W | 82-86 | OT |
| 2021-02-04 | @ | Austin Peay | L | 79-94 | |
| 2021-02-06 | @ | Murray St. | L | 64-76 | |
| 2021-02-08 | vs. | SIUE | W | 74-78 | |
| 2021-02-11 | vs. | Belmont | L | 92-74 | |
| 2021-02-13 | vs. | Tennessee St. | W | 73-93 | |
| 2021-02-15 | vs. | Tennessee Tech | W | 72-83 | |
| 2021-02-18 | vs. | UT Martin | W | 72-89 | |
| 2021-02-20 | vs. | Southeast Mo. St. | L | 94-72 | |
| 2021-02-22 | vs. | Southeast Mo. St. | W | 65-87 | |
| 2021-02-25 | @ | Belmont | W | 81-67 | |
| 2021-02-27 | @ | Tennessee St. | W | 89-84 | |
| 2021-03-04 | @ | Austin Peay | W | 70-67 | |
| 2021-03-05 | vs. | Morehead St. | L | 67-64 |