| 2020-12-23 | @ | Western Ill. | W | 91-72 | |
| 2020-12-27 | vs. | Providence | L | 95-90 | 2OT |
| 2020-12-30 | vs. | UConn | L | 82-61 | |
| 2021-01-09 | @ | Seton Hall | L | 68-76 | |
| 2021-01-11 | @ | UConn | L | 53-60 | |
| 2021-01-16 | @ | Valparaiso | W | 77-58 | |
| 2021-01-19 | @ | Butler | L | 53-67 | |
| 2021-01-23 | vs. | Marquette | |||
| 2021-01-27 | @ | St. John's (NY) | |||
| 2021-01-30 | @ | Creighton | |||
| 2021-02-03 | @ | Xavier | |||
| 2021-02-06 | vs. | Butler | |||
| 2021-02-09 | vs. | Villanova | |||
| 2021-02-11 | vs. | Xavier |