| 2020-11-29 | @ | North Dakota St. | W | 69-58 | |
| 2020-12-01 | @ | Omaha | W | 94-67 | |
| 2020-12-04 | @ | Kennesaw St. | W | 93-58 | |
| 2020-12-08 | vs. | Kansas | L | 73-72 | |
| 2020-12-11 | @ | Nebraska | W | 98-74 | |
| 2020-12-14 | @ | Marquette | L | 84-89 | |
| 2020-12-17 | vs. | St. John's (NY) | W | 76-94 | |
| 2020-12-20 | vs. | UConn | W | 74-76 | OT |
| 2020-12-23 | @ | Xavier | W | 66-61 | |
| 2021-01-02 | vs. | Providence | W | 65-67 | |
| 2021-01-06 | @ | Seton Hall | W | 89-53 | |
| 2021-01-09 | @ | St. John's (NY) | W | 97-79 | |
| 2021-01-16 | vs. | Butler | L | 70-66 | OT |
| 2021-01-20 | @ | Providence | |||
| 2021-01-23 | @ | UConn | |||
| 2021-01-27 | vs. | Seton Hall | |||
| 2021-01-30 | vs. | DePaul | |||
| 2021-02-03 | @ | Georgetown | |||
| 2021-02-06 | vs. | Marquette | |||
| 2021-02-09 | vs. | Georgetown |