| 2020-11-25 | @ | Ohio | L | 61-84 | |
| 2020-11-26 | vs. | Illinois | L | 97-38 | |
| 2020-11-27 | @ | North Carolina A&T | L | 44-74 | |
| 2020-12-03 | vs. | Eastern Ill. | L | 78-56 | |
| 2020-12-05 | vs. | Northwestern | L | 111-66 | |
| 2020-12-09 | vs. | Loyola Chicago | L | 88-51 | |
| 2020-12-15 | vs. | Illinois St. | L | 91-62 | |
| 2020-12-18 | vs. | Northern Ill. | L | 64-54 | |
| 2020-12-20 | vs. | Drake | L | 111-67 |