| 2020-11-30 | vs. | Tennessee Tech | W | 54-62 | |
| 2020-12-05 | @ | Northern Ky. | W | 79-72 | |
| 2020-12-07 | vs. | Middle Tenn. | W | 70-80 | |
| 2020-12-09 | vs. | Bellarmine | W | 68-77 | |
| 2020-12-16 | @ | UNC Asheville | W | 69-66 | |
| 2020-12-19 | vs. | UAB | W | 66-69 | |
| 2020-12-22 | vs. | Tennessee St. | W | 63-66 | |
| 2020-12-30 | @ | Furman | L | 73-77 | |
| 2021-01-02 | vs. | VMI | L | 84-79 | |
| 2021-01-06 | @ | Samford | W | 73-68 | |
| 2021-01-09 | vs. | The Citadel | L | 92-87 | |
| 2021-01-13 | @ | Mercer | W | 83-80 | |
| 2021-01-16 | @ | Wofford | L | 59-77 | |
| 2021-01-20 | vs. | Samford | W | 64-70 | |
| 2021-01-23 | @ | UNCG | L | 66-74 | |
| 2021-02-03 | vs. | Western Caro. | W | 67-74 | |
| 2021-02-06 | vs. | ETSU | W | 65-67 | |
| 2021-02-10 | vs. | Wofford | W | 66-78 | |
| 2021-02-13 | @ | The Citadel | W | 70-66 | |
| 2021-02-15 | @ | ETSU | W | 53-51 | |
| 2021-02-17 | @ | Western Caro. | W | 89-81 | OT |
| 2021-02-20 | vs. | UNCG | L | 60-55 | |
| 2021-02-24 | vs. | Mercer | L | 81-77 | OT |
| 2021-03-06 | @ | ETSU | L | 53-63 |