| 2020-12-04 | vs. | Memphis | L | 85-68 | |
| 2020-12-06 | vs. | Little Rock | L | 86-83 | |
| 2020-12-08 | vs. | Saint Louis | L | 88-65 | |
| 2020-12-12 | vs. | Arkansas | L | 100-75 | |
| 2020-12-14 | vs. | Ole Miss | L | 68-54 | |
| 2020-12-16 | vs. | Mississippi St. | L | 81-65 | |
| 2020-12-29 | vs. | Baylor | L | 93-56 | |
| 2021-01-02 | vs. | McNeese | W | 67-81 | |
| 2021-01-06 | @ | New Orleans | W | 83-79 | |
| 2021-01-09 | @ | Sam Houston St. | L | 80-91 | |
| 2021-01-13 | vs. | SFA | L | 95-69 | |
| 2021-01-16 | @ | Nicholls St. | L | 72-74 | |
| 2021-01-23 | vs. | Abilene Christian | L | 93-58 | |
| 2021-01-27 | vs. | Southeastern La. | L | 69-57 | |
| 2021-01-30 | @ | Northwestern St. | L | 77-81 | |
| 2021-02-06 | @ | McNeese | L | 70-80 | |
| 2021-02-13 | vs. | Sam Houston St. | L | 97-57 | |
| 2021-02-20 | vs. | Nicholls St. | L | 79-68 | |
| 2021-02-22 | vs. | New Orleans | L | 88-63 | |
| 2021-02-27 | @ | Abilene Christian | W | 84-82 | |
| 2021-03-01 | @ | SFA | L | 66-79 | |
| 2021-03-03 | @ | Southeastern La. | W | 88-71 | |
| 2021-03-06 | vs. | Northwestern St. | L | 79-70 |