| 2020-11-27 | vs. | Towson | W | 65-74 | |
| 2020-11-28 | vs. | Army | L | 78-74 | |
| 2020-12-06 | vs. | Bowling Green | L | 86-78 | |
| 2020-12-15 | vs. | Miami (OH) | W | 62-90 | |
| 2020-12-19 | vs. | Syracuse | L | 107-96 | OT |
| 2021-01-09 | @ | Ball St. | W | 86-69 | |
| 2021-01-12 | vs. | Western Mich. | W | 69-85 | |
| 2021-01-15 | @ | Bowling Green | L | 69-76 | |
| 2021-01-19 | vs. | Kent St. | L | 84-81 | |
| 2021-01-21 | @ | Eastern Mich. | W | 92-77 | |
| 2021-01-29 | @ | Ohio | L | 75-76 | |
| 2021-02-02 | vs. | Ball St. | W | 58-78 | |
| 2021-02-06 | @ | Miami (OH) | W | 88-64 | |
| 2021-02-12 | @ | Western Mich. | W | 86-54 | |
| 2021-02-19 | @ | Toledo | L | 70-80 | |
| 2021-02-23 | vs. | Northern Ill. | W | 74-102 | |
| 2021-02-25 | @ | Central Mich. | W | 85-73 | |
| 2021-02-27 | vs. | Ohio | W | 66-86 | |
| 2021-03-02 | @ | Akron | W | 80-78 | |
| 2021-03-05 | @ | Kent St. | W | 81-67 | |
| 2021-03-11 | @ | Miami (OH) | W | 74-63 | |
| 2021-03-12 | @ | Akron | W | 81-74 | OT |
| 2021-03-19 | vs. | Colorado St. | L | 75-73 |