| 2020-11-25 | @ | ETSU | W | 70-47 | |
| 2020-11-27 | vs. | Austin Peay | W | 72-80 | |
| 2020-11-28 | @ | Omaha | W | 70-58 | |
| 2020-12-05 | @ | Tarleton St. | W | 69-48 | |
| 2020-12-09 | vs. | Texas Tech | L | 51-44 | |
| 2020-12-22 | vs. | Arkansas | L | 85-72 | |
| 2021-01-02 | @ | Lamar University | W | 83-65 | |
| 2021-01-06 | vs. | Houston Baptist | W | 63-66 | |
| 2021-01-16 | @ | Southeastern La. | W | 76-42 | |
| 2021-01-20 | vs. | Sam Houston St. | L | 64-57 | |
| 2021-01-23 | @ | Central Ark. | W | 93-58 | |
| 2021-01-27 | @ | SFA | W | 82-62 | |
| 2021-02-06 | vs. | Lamar University | W | 62-77 | |
| 2021-02-08 | vs. | TX A&M-Corpus Christi | W | 69-82 | |
| 2021-02-10 | @ | Houston Baptist | W | 88-59 | |
| 2021-02-13 | @ | TX A&M-Corpus Christi | W | 83-55 | |
| 2021-02-24 | @ | Sam Houston St. | W | 86-72 | |
| 2021-02-27 | vs. | Central Ark. | L | 84-82 | |
| 2021-03-03 | vs. | SFA | W | 61-63 | |
| 2021-03-12 | @ | Lamar University | W | 93-71 | |
| 2021-03-20 | vs. | Texas | W | 52-53 | |
| 2021-03-22 | vs. | UCLA | L | 67-47 |